A Zinc Ion Controls Assembly and Stability of the Major Capsid Protein of Rotavirus

The recent determination of the crystal structure of VP6, the major capsid protein of rotavirus, revealed a trimer containing a central zinc ion coordinated by histidine 153 from each of the three subunits. The role of the zinc ion in the functions of VP6 was investigated by site-directed mutagenesi...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Erk, Inge, Huet, Jean-Claude, Duarte, Mariela, Duquerroy, Stéphane, Rey, Felix, Cohen, Jean, Lepault, Jean
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Structure and Assembly
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12610135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.6.3595-3601.2003
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