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A Zinc Ion Controls Assembly and Stability of the Major Capsid Protein of Rotavirus
The recent determination of the crystal structure of VP6, the major capsid protein of rotavirus, revealed a trimer containing a central zinc ion coordinated by histidine 153 from each of the three subunits. The role of the zinc ion in the functions of VP6 was investigated by site-directed mutagenesi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149495/ https://ncbi.nlm.nih.gov/pubmed/12610135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3595-3601.2003 |
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