A Zinc Ion Controls Assembly and Stability of the Major Capsid Protein of Rotavirus

The recent determination of the crystal structure of VP6, the major capsid protein of rotavirus, revealed a trimer containing a central zinc ion coordinated by histidine 153 from each of the three subunits. The role of the zinc ion in the functions of VP6 was investigated by site-directed mutagenesi...

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Bibliografiska uppgifter
Huvudupphovsmän: Erk, Inge, Huet, Jean-Claude, Duarte, Mariela, Duquerroy, Stéphane, Rey, Felix, Cohen, Jean, Lepault, Jean
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2003
Ämnen:
Structure and Assembly
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC149495/
https://ncbi.nlm.nih.gov/pubmed/12610135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.6.3595-3601.2003
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