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The Phospholipid Transfer Protein Gene Is a Liver X Receptor Target Expressed by Macrophages in Atherosclerotic Lesions

The liver X receptors (LXRs) are members of the nuclear receptor superfamily that are activated by oxysterols. In response to ligand binding, LXRs regulate a variety of genes involved in the catabolism, transport, and uptake of cholesterol and its metabolites. Here we demonstrate that LXRs also regu...

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Detalhes bibliográficos
Main Authors: Laffitte, Bryan A., Joseph, Sean B., Chen, Mingyi, Castrillo, Antonio, Repa, Joyce, Wilpitz, Damien, Mangelsdorf, David, Tontonoz, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC149472/
https://ncbi.nlm.nih.gov/pubmed/12612088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.6.2182-2191.2003
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