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Resistance Genes of Aminocoumarin Producers: Two Type II Topoisomerase Genes Confer Resistance against Coumermycin A(1) and Clorobiocin

The aminocoumarin resistance genes of the biosynthetic gene clusters of novobiocin, coumermycin A(1), and clorobiocin were investigated. All three clusters contained a gyrB(R) resistance gene, coding for a gyrase B subunit. Unexpectedly, the clorobiocin and the coumermycin A(1) clusters were found t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schmutz, Elisabeth, Mühlenweg, Agnes, Li, Shu-Ming, Heide, Lutz
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC149333/
https://ncbi.nlm.nih.gov/pubmed/12604514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.3.869-877.2003
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