Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplex-forming oligonucleotide

The transcription factor Ets2 has a role in cancer development and represents an attractive therapeutic target. In this study, we designed a triplex-forming oligonucleotide (TFO) directed to a homopurine:homopyrimidine sequence in the Ets2 promoter. Transcription factors of the Sp family bound to th...

Full description

Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Carbone, Giuseppina M., McGuffie, Eileen M., Collier, Angela, Catapano, Carlo V.
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2003
Subjects:	Articles
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149218/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12560478/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg198
Tags:	Add Tag No Tags, Be the first to tag this record!