Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplex-forming oligonucleotide
The transcription factor Ets2 has a role in cancer development and represents an attractive therapeutic target. In this study, we designed a triplex-forming oligonucleotide (TFO) directed to a homopurine:homopyrimidine sequence in the Ets2 promoter. Transcription factors of the Sp family bound to th...
Tallennettuna:
| Julkaisussa: | Nucleic Acids Res |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2003
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149218/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12560478/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg198 |
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