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Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplex-forming oligonucleotide

The transcription factor Ets2 has a role in cancer development and represents an attractive therapeutic target. In this study, we designed a triplex-forming oligonucleotide (TFO) directed to a homopurine:homopyrimidine sequence in the Ets2 promoter. Transcription factors of the Sp family bound to th...

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Библиографические подробности
Главные авторы: Carbone, Giuseppina M., McGuffie, Eileen M., Collier, Angela, Catapano, Carlo V.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC149218/
https://ncbi.nlm.nih.gov/pubmed/12560478
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