Selective inhibition of transcription of the Ets2 gene in prostate cancer cells by a triplex-forming oligonucleotide

The transcription factor Ets2 has a role in cancer development and represents an attractive therapeutic target. In this study, we designed a triplex-forming oligonucleotide (TFO) directed to a homopurine:homopyrimidine sequence in the Ets2 promoter. Transcription factors of the Sp family bound to th...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Carbone, Giuseppina M., McGuffie, Eileen M., Collier, Angela, Catapano, Carlo V.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2003
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149218/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12560478/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg198
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