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Cloning of human centromeres by transformation-associated recombination in yeast and generation of functional human artificial chromosomes

Human centromeres remain poorly characterized regions of the human genome despite their importance for the maintenance of chromosomes. In part this is due to the difficulty of cloning of highly repetitive DNA fragments and distinguishing chromosome-specific clones in a genomic library. In this work...

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Published in:Nucleic Acids Res
Main Authors: Kouprina, N., Ebersole, T., Koriabine, M., Pak, E., Rogozin, I. B., Katoh, M., Oshimura, M., Ogi, K., Peredelchuk, M., Solomon, G., Brown, W., Barrett, J. C., Larionov, V.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149202/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12560488/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg182
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