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Cloning of human centromeres by transformation-associated recombination in yeast and generation of functional human artificial chromosomes

Human centromeres remain poorly characterized regions of the human genome despite their importance for the maintenance of chromosomes. In part this is due to the difficulty of cloning of highly repetitive DNA fragments and distinguishing chromosome-specific clones in a genomic library. In this work...

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Auteurs principaux: Kouprina, N., Ebersole, T., Koriabine, M., Pak, E., Rogozin, I. B., Katoh, M., Oshimura, M., Ogi, K., Peredelchuk, M., Solomon, G., Brown, W., Barrett, J. C., Larionov, V.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC149202/
https://ncbi.nlm.nih.gov/pubmed/12560488
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