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Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression
TEL is a transcriptional repressor that is a frequent target of chromosomal translocations in a large number of hematalogical malignancies. These rearrangements fuse a potent oligomerization module, the SAM domain of TEL, to a variety of tyrosine kinases or transcriptional regulatory proteins. The s...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149168/ https://ncbi.nlm.nih.gov/pubmed/11483520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4173 |
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