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Native interface of the SAM domain polymer of TEL

BACKGROUND: TEL is a transcriptional repressor containing a SAM domain that forms a helical polymer. In a number of hematologic malignancies, chromosomal translocations lead to aberrant fusions of TEL-SAM to a variety of other proteins, including many tyrosine kinases. TEL-SAM polymerization results...

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Detalhes bibliográficos
Main Authors: Tran, Hoang H, Kim, Chongwoo A, Faham, Salem, Siddall, Marie-Claire, Bowie, James U
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126206/
https://ncbi.nlm.nih.gov/pubmed/12193272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-2-5
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