Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil–DNA glycosylase

Gene-targeted mice deficient in the evolutionarily conserved uracil–DNA glycosylase encoded by the UNG gene surprisingly lack the mutator phenotype characteristic of bacterial and yeast ung(–) mutants. A complementary uracil–DNA glycosylase activity detected in ung(–/–) murine cells and tissues may...

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Pubblicato in:	EMBO J
Autori principali:	Nilsen, Hilde, Haushalter, Karl A., Robins, Peter, Barnes, Deborah E., Verdine, Gregory L., Lindahl, Tomas
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483530/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.15.4278
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