Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil–DNA glycosylase

Gene-targeted mice deficient in the evolutionarily conserved uracil–DNA glycosylase encoded by the UNG gene surprisingly lack the mutator phenotype characteristic of bacterial and yeast ung(–) mutants. A complementary uracil–DNA glycosylase activity detected in ung(–/–) murine cells and tissues may...

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Autors principals: Nilsen, Hilde, Haushalter, Karl A., Robins, Peter, Barnes, Deborah E., Verdine, Gregory L., Lindahl, Tomas
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC149160/
https://ncbi.nlm.nih.gov/pubmed/11483530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4278
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