Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil–DNA glycosylase
Gene-targeted mice deficient in the evolutionarily conserved uracil–DNA glycosylase encoded by the UNG gene surprisingly lack the mutator phenotype characteristic of bacterial and yeast ung(–) mutants. A complementary uracil–DNA glycosylase activity detected in ung(–/–) murine cells and tissues may...
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| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2001
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11483530/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.15.4278 |
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