Wird geladen...
Converting a DNA damage checkpoint effector (UmuD(2)C) into a lesion bypass polymerase (UmuD′(2)C)
During the SOS response of Escherichia coli to DNA damage, the umuDC operon is induced, producing the trimeric protein complexes UmuD(2)C, a DNA damage checkpoint effector, and UmuD′(2)C (DNA polymerase V), which carries out translesion synthesis, the basis of ‘SOS mutagenesis’. UmuD′(2), the homodi...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2001
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149154/ https://ncbi.nlm.nih.gov/pubmed/11483531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4287 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|