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Converting a DNA damage checkpoint effector (UmuD(2)C) into a lesion bypass polymerase (UmuD′(2)C)

During the SOS response of Escherichia coli to DNA damage, the umuDC operon is induced, producing the trimeric protein complexes UmuD(2)C, a DNA damage checkpoint effector, and UmuD′(2)C (DNA polymerase V), which carries out translesion synthesis, the basis of ‘SOS mutagenesis’. UmuD′(2), the homodi...

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Bibliografski detalji
Glavni autori: Ferentz, Ann E., Walker, Graham C., Wagner, Gerhard
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC149154/
https://ncbi.nlm.nih.gov/pubmed/11483531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4287
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