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Converting a DNA damage checkpoint effector (UmuD(2)C) into a lesion bypass polymerase (UmuD′(2)C)
During the SOS response of Escherichia coli to DNA damage, the umuDC operon is induced, producing the trimeric protein complexes UmuD(2)C, a DNA damage checkpoint effector, and UmuD′(2)C (DNA polymerase V), which carries out translesion synthesis, the basis of ‘SOS mutagenesis’. UmuD′(2), the homodi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149154/ https://ncbi.nlm.nih.gov/pubmed/11483531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4287 |
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