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Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle

We have examined the behavior of pre-replication complex (pre-RC) proteins in relation to key cell cycle transitions in Chinese Hamster Ovary (CHO) cells. ORC1, ORC4 and Cdc6 were stable (T(1/2) >2 h) and associated with a chromatin-containing fraction throughout the cell cycle. Green fluorescent...

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Bibliografiska uppgifter
Huvudupphovsmän: Okuno, Yukiko, McNairn, Adrian J., den Elzen, Nicole, Pines, Jonathon, Gilbert, David M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2001
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC149150/
https://ncbi.nlm.nih.gov/pubmed/11483529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4263
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