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Cyclin a Is Destroyed in Prometaphase and Can Delay Chromosome Alignment and Anaphase

Mitosis is controlled by the specific and timely degradation of key regulatory proteins, notably the mitotic cyclins that bind and activate the cyclin-dependent kinases (Cdks). In animal cells, cyclin A is always degraded before cyclin B, but the exact timing and the mechanism underlying this are no...

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Detalhes bibliográficos
Main Authors: den Elzen, Nicole, Pines, Jonathon
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185531/
https://ncbi.nlm.nih.gov/pubmed/11285279
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