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Cyclin a Is Destroyed in Prometaphase and Can Delay Chromosome Alignment and Anaphase

Mitosis is controlled by the specific and timely degradation of key regulatory proteins, notably the mitotic cyclins that bind and activate the cyclin-dependent kinases (Cdks). In animal cells, cyclin A is always degraded before cyclin B, but the exact timing and the mechanism underlying this are no...

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Autori principali: den Elzen, Nicole, Pines, Jonathon
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185531/
https://ncbi.nlm.nih.gov/pubmed/11285279
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