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Stability, chromatin association and functional activity of mammalian pre-replication complex proteins during the cell cycle
We have examined the behavior of pre-replication complex (pre-RC) proteins in relation to key cell cycle transitions in Chinese Hamster Ovary (CHO) cells. ORC1, ORC4 and Cdc6 were stable (T(1/2) >2 h) and associated with a chromatin-containing fraction throughout the cell cycle. Green fluorescent...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149150/ https://ncbi.nlm.nih.gov/pubmed/11483529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4263 |
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