NEDD8 recruits E2-ubiquitin to SCF E3 ligase

NEDD8/Rub1 is a ubiquitin (Ub)-like post-translational modifier that is covalently linked to cullin (Cul)-family proteins in a manner analogous to ubiquitylation. NEDD8 is known to enhance the ubiquitylating activity of the SCF complex (composed of Skp1, Cul-1, ROC1 and F-box protein), but the mecha...

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Autores principales: Kawakami, Takayuki, Chiba, Tomoki, Suzuki, Toshiaki, Iwai, Kazuhiro, Yamanaka, Koji, Minato, Nagahiro, Suzuki, Hiroshi, Shimbara, Naoki, Hidaka, Yuko, Osaka, Fumio, Omata, Masao, Tanaka, Keiji
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2001
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC149148/
https://ncbi.nlm.nih.gov/pubmed/11483504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.15.4003
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