Roles of Mycobacterium smegmatis d-Alanine:d-Alanine Ligase and d-Alanine Racemase in the Mechanisms of Action of and Resistance to the Peptidoglycan Inhibitor d-Cycloserine
d-Cycloserine (DCS) targets the peptidoglycan biosynthetic enzymes d-alanine racemase (Alr) and d-alanine:d-alanine ligase (Ddl). Previously, we demonstrated that the overproduction of Alr in Mycobacterium smegmatis determines a DCS resistance phenotype. In this study, we investigated the roles of b...
Gespeichert in:
| Veröffentlicht in: | Antimicrob Agents Chemother |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2003
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149019/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12499203/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.1.283-291.2003 |
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