The Antimalarial Artemisinin Synergizes with Antibiotics To Protect against Lethal Live Escherichia coli Challenge by Decreasing Proinflammatory Cytokine Release

In the present study artemisinin (ART) was found to have potent anti-inflammatory effects in animal models of sepsis induced by CpG-containing oligodeoxy-nucleotides (CpG ODN), lipopolysaccharide (LPS), heat-killed Escherichia coli 35218 or live E. coli. Furthermore, we found that ART protected mice...

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Detalles Bibliográficos
Main Authors: Wang, Jun, Zhou, Hong, Zheng, Jiang, Cheng, Juan, Liu, Wei, Ding, Guofu, Wang, Liangxi, Luo, Ping, Lu, Yongling, Cao, Hongwei, Yu, Shuangjiang, Li, Bin, Zhang, Lezhi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Experimental Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489802/
https://ncbi.nlm.nih.gov/pubmed/16801421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01066-05
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