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Pharmacokinetics of Unbound Linezolid in Plasma and Tissue Interstitium of Critically Ill Patients after Multiple Dosing Using Microdialysis

The antimicrobial agent linezolid is approved for the treatment of severe infections caused by, e.g., methicillin-resistant Staphylococcus strains. In order to evaluate the penetration of linezolid into the interstitial space fluid (ISF) of subcutaneous adipose tissue and skeletal muscle of the targ...

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Main Authors: Buerger, Cornelia, Plock, Nele, Dehghanyar, Pejman, Joukhadar, Christian, Kloft, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489800/
https://ncbi.nlm.nih.gov/pubmed/16801426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01468-05
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