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Role of Tumor Necrosis Factor Alpha in Development of Immunity against Cryptosporidium parvum Infection

Tumor necrosis factor (TNF-α) significantly reduced Cryptosporidium parvum development in a murine enterocyte cell line, and a key mechanism of action appeared to be inhibition of parasite invasion. However, TNF-α-deficient mice controlled infection as effectively as wild-type mice. This suggests th...

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Détails bibliographiques
Auteurs principaux: Lean, I-Sarah, Lacroix-Lamandé, Sonia, Laurent, Fabrice, McDonald, Vincent
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489749/
https://ncbi.nlm.nih.gov/pubmed/16790816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00195-06
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