Cryptosporidium parvum-Specific Mucosal Immune Response in C57BL/6 Neonatal and Gamma Interferon-Deficient Mice: Role of Tumor Necrosis Factor Alpha in Protection

Both neonatal and C57BL/6 gamma interferon (IFN-γ) knockout (C57BL/6-GKO) mice are susceptible to Cryptosporidium parvum, but the course of infection is different. Neonatal mice are able to clear the parasite within 3 weeks, whereas C57BL/6-GKO mice, depending on age, die rapidly or remain chronical...

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Bibliographic Details
Main Authors: Lacroix, Sonia, Mancassola, Roselyne, Naciri, Muriel, Laurent, Fabrice
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC98067/
https://ncbi.nlm.nih.gov/pubmed/11179338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.3.1635-1642.2001
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