Blinded, Multicenter Comparison of Methods To Detect a Drug-Resistant Mutant of Human Immunodeficiency Virus Type 1 at Low Frequency

We determined the abilities of 10 technologies to detect and quantify a common drug-resistant mutant of human immunodeficiency virus type 1 (lysine to asparagine at codon 103 of the reverse transcriptase) using a blinded test panel containing mutant-wild-type mixtures ranging from 0.01% to 100% muta...

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Autori principali: Halvas, Elias K., Aldrovandi, Grace M., Balfe, Peter, Beck, Ingrid A., Boltz, Valerie F., Coffin, John M., Frenkel, Lisa M., Hazelwood, J. Darren, Johnson, Victoria A., Kearney, Mary, Kovacs, Andrea, Kuritzkes, Daniel R., Metzner, Karin J., Nissley, Dwight V., Nowicki, Marek, Palmer, Sarah, Ziermann, Rainer, Zhao, Richard Y., Jennings, Cheryl L., Bremer, James, Brambilla, Don, Mellors, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
Soggetti:
Virology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489464/
https://ncbi.nlm.nih.gov/pubmed/16825395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00449-06
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