Sphingosine-1-Phosphate Phosphohydrolase Regulates Endoplasmic Reticulum-to-Golgi Trafficking of Ceramide

Previous studies demonstrated that sphingosine-1-phosphate (S1P) phosphohydrolase 1 (SPP-1), which is located mainly in the endoplasmic reticulum (ER), regulates sphingolipid metabolism and apoptosis (H. Le Stunff et al., J. Cell Biol. 158:1039-1049, 2002). We show here that the treatment of SPP-1-o...

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Main Authors: Giussani, Paola, Maceyka, Michael, Le Stunff, Hervé, Mikami, Aki, Lépine, Sandrine, Wang, Elaine, Kelly, Samuel, Merrill, Alfred H., Milstien, Sheldon, Spiegel, Sarah
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2006
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489178/
https://ncbi.nlm.nih.gov/pubmed/16782891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02107-05
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