Essential Role of Pten in Body Size Determination and Pancreatic β-Cell Homeostasis In Vivo

PTEN (phosphatase with tensin homology) is a potent negative regulator of phosphoinositide 3-kinase (PI3K)/Akt signaling, an evolutionarily conserved pathway that signals downstream of growth factors, including insulin and insulin-like growth factor 1. In lower organisms, this pathway participates i...

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Detalhes bibliográficos
Main Authors: Nguyen, Kinh-Tung T., Tajmir, Panteha, Lin, Chia Hung, Liadis, Nicole, Zhu, Xu-Dong, Eweida, Mohammed, Tolasa-Karaman, Gunce, Cai, Fang, Wang, Rennian, Kitamura, Tadahiro, Belsham, Denise D., Wheeler, Michael B., Suzuki, Akira, Mak, Tak W., Woo, Minna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489140/
https://ncbi.nlm.nih.gov/pubmed/16738317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00238-06
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