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Identification and Characterization of a Gain-of-Function RAG-1 Mutant
RAG-1 and RAG-2 initiate V(D)J recombination by cleaving DNA at recombination signal sequences through sequential nicking and transesterification reactions to yield blunt signal ends and coding ends terminating in a DNA hairpin structure. Ubiquitous DNA repair factors then mediate the rejoining of b...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1489120/ https://ncbi.nlm.nih.gov/pubmed/16738334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02487-05 |
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