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GAS41 Is Required for Repression of the p53 Tumor Suppressor Pathway during Normal Cellular Proliferation

GAS41 is a common subunit of the TIP60 and SRCAP complexes and is essential for cell growth and viability. Here, we report that GAS41 is required for repression of the p53 tumor suppressor pathway during normal cellular proliferation. Either GAS41 small interfering RNA-mediated knockdown of GAS41 ex...

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Detalhes bibliográficos
Main Authors: Park, Jeong Hyeon, Roeder, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489109/
https://ncbi.nlm.nih.gov/pubmed/16705155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02185-05
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