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GAS41 Is Required for Repression of the p53 Tumor Suppressor Pathway during Normal Cellular Proliferation

GAS41 is a common subunit of the TIP60 and SRCAP complexes and is essential for cell growth and viability. Here, we report that GAS41 is required for repression of the p53 tumor suppressor pathway during normal cellular proliferation. Either GAS41 small interfering RNA-mediated knockdown of GAS41 ex...

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Hlavní autoři: Park, Jeong Hyeon, Roeder, Robert G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489109/
https://ncbi.nlm.nih.gov/pubmed/16705155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02185-05
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