Tissue- and Tumor-Specific Targeting of Murine Leukemia Virus-Based Replication-Competent Retroviral Vectors

Replication-competent retrovirus vectors based on murine leukemia virus (MLV) have been shown to effectively transfer therapeutic genes over multiple serial infections in cell culture and through solid tumors in vivo with a high degree of genomic stability. While simple retroviruses possess a natura...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Metzl, Christian, Mischek, Daniela, Salmons, Brian, Günzburg, Walter H., Renner, Matthias, Portsmouth, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Gene Delivery
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489065/
https://ncbi.nlm.nih.gov/pubmed/16809312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00020-06
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