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Modest but Reproducible Inhibition of Human Immunodeficiency Virus Type 1 Infection in Macrophages following LEDGFp75 Silencing

LEDGFp75 is a cellular protein which binds human immunodeficiency virus type 1 (HIV-1) integrase with high specificity and affinity but whose function in infection has not been defined. We infected LEDGFp75-deficient primary macrophages with wild-type HIV in order to assess potential infection pheno...

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Autori principali: Zielske, Steven P., Stevenson, Mario
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489053/
https://ncbi.nlm.nih.gov/pubmed/16809334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02470-05
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