Vpx Is Critical for Reverse Transcription of the Human Immunodeficiency Virus Type 2 Genome in Macrophages

The abilities of wild-type and vpx-defective human immunodeficiency virus type 2 (HIV-2) clones to synthesize viral DNA in human monocyte-derived macrophages (MDMs) and lymphocytic cells were comparatively and quantitatively evaluated. While the vpx-defective mutant directed the synthesis of viral D...

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Detalhes bibliográficos
Main Authors: Fujita, Mikako, Otsuka, Masami, Miyoshi, Masami, Khamsri, Boonruang, Nomaguchi, Masako, Adachi, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493314/
https://ncbi.nlm.nih.gov/pubmed/18495778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01003-07
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