Role of Invariant Thr80 in Human Immunodeficiency Virus Type 1 Protease Structure, Function, and Viral Infectivity

Sequence variability associated with human immunodeficiency virus type 1 (HIV-1) is useful for inferring structural and/or functional constraints at specific residues within the viral protease. Positions that are invariant even in the presence of drug selection define critically important residues f...

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Detalhes bibliográficos
Main Authors: Foulkes, Jennifer E., Prabu-Jeyabalan, Moses, Cooper, Deyna, Henderson, Gavin J., Harris, Janera, Swanstrom, Ronald, Schiffer, Celia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489026/
https://ncbi.nlm.nih.gov/pubmed/16809296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01900-05
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