Furin-, ADAM 10-, and γ-Secretase-Mediated Cleavage of a Receptor Tyrosine Phosphatase and Regulation of β-Catenin's Transcriptional Activity

Several receptor protein tyrosine phosphatases (RPTPs) are cell adhesion molecules involved in homophilic interactions, suggesting that RPTP outside-in signaling is coupled to cell contact formation. However, little is known about the mechanisms by which cell density regulates RPTP function. We show...

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Detalhes bibliográficos
Main Authors: Anders, Lars, Mertins, Philipp, Lammich, Sven, Murgia, Marta, Hartmann, Dieter, Saftig, Paul, Haass, Christian, Ullrich, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1489012/
https://ncbi.nlm.nih.gov/pubmed/16648485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.10.3917-3934.2006
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