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ADAM10 cleavage of N-cadherin and regulation of cell–cell adhesion and β-catenin nuclear signalling
Cadherins are critically involved in tissue development and tissue homeostasis. We demonstrate here that neuronal cadherin (N-cadherin) is cleaved specifically by the disintegrin and metalloproteinase ADAM10 in its ectodomain. ADAM10 is not only responsible for the constitutive, but also for the reg...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549617/ https://ncbi.nlm.nih.gov/pubmed/15692570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600548 |
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