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Articular Chondrocytes Express the Receptor for Advanced Glycation End Products: Potential Role in Osteoarthritis

OBJECTIVE: The receptor for advanced glycation end products (RAGE) binds multiple ligands, including S100 proteins, high mobility group box chromosomal protein 1 (HMGB-1), and AGEs, all of which are present in articular cartilage. Stimulation of RAGE signaling can lead to MAP kinase activation and i...

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Autors principals: Loeser, Richard F., Yammani, Raghunatha R., Carlson, Cathy S., Chen, Hong, Cole, Ada, Im, Hee-Jeong, Bursch, Laura S., Yan, Shi Du
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1488730/
https://ncbi.nlm.nih.gov/pubmed/16052547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.21199
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