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Amino Acid Sequence Requirements in the Hinge of Human Immunoglobulin A1 (IgA1) for Cleavage by Streptococcal IgA1 Proteases

The amino acid sequence requirements in the hinge of human immunoglobulin A1 (IgA1) for cleavage by IgA1 proteases of different species of Streptococcus were investigated. Recombinant IgA1 antibodies were generated with point mutations at proline 227 and threonine 228, the residues lying on either s...

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Uloženo v:
Vydáno v:Infect Immun
Hlavní autoři: Batten, Margaret R., Senior, Bernard W., Kilian, Mogens, Woof, Jenny M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148859/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12595464/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.3.1462-1469.2003
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