Werner syndrome helicase contains a 5'-->3' exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding.
We show that WRN helicase contains a unique 5'-->3' exonuclease activity in the N-terminal region. Adeletion mutant lacking 231 N-terminal amino acid residues, made in a baculovirus system, did nothave this activity, while it showed ATPase and DNA helicase activities. This exonuclease activity was c...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1999
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148803/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10325426/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.11.2361 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|