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Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein.

Ku protein and the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are essential components of the double-strand break repair machinery in higher eukaryotic cells. Ku protein binds to broken DNA ends and recruits DNA-PKcs to form an enzymatically active complex. To characterize the arrange...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Yoo, S, Dynan, W S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148766/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10572166/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.24.4679
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