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Improved fidelity of thermostable ligases for detection of microsatellite repeat sequences using nucleoside analogs.

Microsatellite repeats consisting of dinucleotide sequences are ubiquitous in the human genome and have proven useful for linkage analysis, positional cloning and forensic identification purposes. In this study, the potential of utilizing the ligase detection reaction for the analysis of such micros...

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Bibliografiske detaljer
Main Authors: Zirvi, M, Bergstrom, D E, Saurage, A S, Hammer, R P, Barany, F
Format: Artigo
Sprog:Inglês
Udgivet: 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC148764/
https://ncbi.nlm.nih.gov/pubmed/10572193
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