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Improved fidelity of thermostable ligases for detection of microsatellite repeat sequences using nucleoside analogs.

Microsatellite repeats consisting of dinucleotide sequences are ubiquitous in the human genome and have proven useful for linkage analysis, positional cloning and forensic identification purposes. In this study, the potential of utilizing the ligase detection reaction for the analysis of such micros...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Principais autores: Zirvi, M, Bergstrom, D E, Saurage, A S, Hammer, R P, Barany, F
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1999
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148764/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10572193/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.24.e41
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