Chiral and steric effects in the efficient binding of alpha-anomeric deoxyoligonucleoside N-alkylphosphoramidates to ssDNA and RNA.

We report hybridization properties of new phosphate-modified alpha-oligonucleoside analogs with non-ionic or cationic internucleotide linkages such as methoxy-ethylphosphoramidate (PNHME), phosphoromorpholi-date (PMOR) and dimethylaminopropylphosphor-amidate (PNHDMAP). First we evaluated the chirali...

Descripció completa

Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Laurent, A, Naval, M, Debart, F, Vasseur, J J, Rayner, B
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1999
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148688/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.21.4151
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!