Excision of oxidatively damaged DNA bases by the human alpha-hOgg1 protein and the polymorphic alpha-hOgg1(Ser326Cys) protein which is frequently found in human populations.

We have investigated the substrate specificity of the major nuclear form of the human Ogg1 protein, referred as alpha-hOgg1, for excision of damaged bases from DNA exposed to gamma-irradiation. Excision products were identified and quantified using gas chromatography/isotope dilution mass spectromet...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Dherin, C, Radicella, J P, Dizdaroglu, M, Boiteux, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1999
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10497264/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.20.4001
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