Probing the role of structural water in a duplex oligodeoxyribonucleotide containing a water-mimicking base analog.

Molecular dynamics simulations were performed on models of the dodecamer DNA double-stranded segment, [d(CGCGAATTCGCG)](2), in which each of the adenine residues, individually or jointly, was replaced by the water-mimicking analog 2'-deoxy-7-(hydroxy-methyl)-7-deazaadenosine (hm(7)c(7)dA) [Rockhill,...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Kosztin, D, Gumport, R I, Schulten, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1999
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10446246/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.17.3550
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