Probing the role of structural water in a duplex oligodeoxyribonucleotide containing a water-mimicking base analog.
Molecular dynamics simulations were performed on models of the dodecamer DNA double-stranded segment, [d(CGCGAATTCGCG)](2), in which each of the adenine residues, individually or jointly, was replaced by the water-mimicking analog 2'-deoxy-7-(hydroxy-methyl)-7-deazaadenosine (hm(7)c(7)dA) [Rockhill,...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10446246/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.17.3550 |
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