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Probing the role of structural water in a duplex oligodeoxyribonucleotide containing a water-mimicking base analog.

Molecular dynamics simulations were performed on models of the dodecamer DNA double-stranded segment, [d(CGCGAATTCGCG)](2), in which each of the adenine residues, individually or jointly, was replaced by the water-mimicking analog 2'-deoxy-7-(hydroxy-methyl)-7-deazaadenosine (hm(7)c(7)dA) [Rockhill,...

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書目詳細資料
發表在:Nucleic Acids Res
Principais autores: Kosztin, D, Gumport, R I, Schulten, K
格式: Artigo
語言:Inglês
出版: Oxford University Press 1999
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148600/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10446246/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.17.3550
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