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Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein.

Myotonic dystrophy (DM) is associated with a (CTG) (n) triplet repeat expansion in the 3'-untranslated region of the myotonic dystrophy protein kinase (DMPK) gene. Using electron microscopy, we visualized large RNAs containing up to 130 CUG repeats and studied the binding of purified CUG-binding pro...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Michalowski, S, Miller, J W, Urbinati, C R, Paliouras, M, Swanson, M S, Griffith, J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148598/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10446244/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.17.3534
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