Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein.

Myotonic dystrophy (DM) is associated with a (CTG) (n) triplet repeat expansion in the 3'-untranslated region of the myotonic dystrophy protein kinase (DMPK) gene. Using electron microscopy, we visualized large RNAs containing up to 130 CUG repeats and studied the binding of purified CUG-bindin...

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Autors principals: Michalowski, S, Miller, J W, Urbinati, C R, Paliouras, M, Swanson, M S, Griffith, J
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC148598/
https://ncbi.nlm.nih.gov/pubmed/10446244
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