Plasmid linking number change induced by topoisomerase I-mediated DNA damage.

The state of cellular chromatin in response to DNA damage has been examined by monitoring the change in the linking number of circular episomes. COS cells transfected with an SV40-based vector were treated with camptothecin (CPT), a eukaryotic DNA topoisomerase I (TOP1) poison which induces TOP1-med...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Duann, P, Sun, M, Lin, C T, Zhang, H, Liu, L F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1999
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10390532/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.14.2905
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